Hepatitis C is a world-wide disease. The HCV infection rate is about 3% (170 million) world-wide and about 3.2% in China and 1.5% in India. Alarming rates were reported for many African nations, reaching as high as 14.5% in Egypt. Acute infection is often asymptomatic or the symptoms are indistinct after the initial infection. About 70-80% of people infected with HCV are unable to clear the virus and become chronically infected, that may further progress to hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC).